4-[(Cyclopropylamino)carbonyl]benzeneboronic acid, 4-Borono-N-cyclopropylbenzamide - Names and Identifiers
4-[(Cyclopropylamino)carbonyl]benzeneboronic acid, 4-Borono-N-cyclopropylbenzamide - Physico-chemical Properties
Molecular Formula | C11H14BNO3
|
Molar Mass | 219.04 |
Density | 1.28g/cm3 |
Melting Point | 202-206°C |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.586 |
4-[(Cyclopropylamino)carbonyl]benzeneboronic acid, 4-Borono-N-cyclopropylbenzamide - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
WGK Germany | 3 |
Hazard Note | Irritant/Keep Cold |
4-[(Cyclopropylamino)carbonyl]benzeneboronic acid, 4-Borono-N-cyclopropylbenzamide - Introduction
4-(Cyclopropylaminocarbonyl)phenylboronic acid is an organic compound with the chemical formula C10H12BNO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4-(Cyclopropylaminocarbonyl)phenylboronic acid is a white to pale yellow solid.
-Solubility: It has limited solubility in water and can be dissolved in organic solvents (such as dimethyl sulfoxide, acetonitrile).
Use:
- 4-(Cyclopropylaminocarbonyl)phenylboronic acid is an important organic synthesis intermediate, commonly used in organic synthesis reactions.
-It is often used in phenylboronic acid coupling reactions to build C- N and C- O bonds.
-in drug research and development, pesticide synthesis and other fields have a wide range of applications.
Preparation Method:
- 4-(Cyclopropylaminocarbonyl)phenylboronic acid can be prepared by the reaction between phenylboronic acid and cyclopropylamine. The specific preparation method may be reacting phenylboronic acid with cyclopropylamine in dimethyl sulfoxide at an appropriate temperature to obtain the target product, followed by crystallization purification.
Safety Information:
- 4-(Cyclopropylaminocarbonyl) Specific safety information for phenylboronic acid requires reference to the laboratory's safety data sheet and use card.
-Wear appropriate protective equipment such as lab gloves, glasses, and lab coats during handling and use.
-Avoid dust and contact with skin, eyes and respiratory tract.
-Read the safety instructions of the compound carefully before use and follow the correct laboratory procedures.
Last Update:2024-04-09 02:00:46